Total Synthesis of Chaetoglobin A via Catalytic, Atroposelective Oxidative Phenol Coupling
نویسندگان
چکیده
منابع مشابه
Synthesis of biaryls via catalytic decarboxylative coupling.
We present a safe and convenient cross-coupling strategy for the large-scale synthesis of biaryls, commercially important structures often found in biologically active molecules. In contrast to traditional cross-couplings, which require the prior preparation of organometallic reagents, we use a copper catalyst to generate the carbon nucleophiles in situ, via decarboxylation of easily accessible...
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ژورنال
عنوان ژورنال: Organic Letters
سال: 2018
ISSN: 1523-7060,1523-7052
DOI: 10.1021/acs.orglett.8b02183